Research and Achievements

Fiscal Year2014

Achievements for Fiscal Year 2014

  1. Kayo H, Kiga K, Fukuda-Yuzawa Y, Hedlund S, Murakami K, De La Rosa-Velazquez IA, Kimura T, Shimoda K, Tanabe M, Fukao T. miR-212 and miR-132 are dispensable for mouse mammary gland development. Nature Genetics 2014;46: 802-804.
    http://dx.doi.org/10.1038/ng.2990.
  2. Asahi H, Tolba MEM, Tanabe M, Sugano S, Abe K, Kawamoto F. Perturbation of copper homeostasis is instrumental in early developmental arrest of intraerythrocytic Plasmodium falciparum. BMC Microbiology 2014;14:167-177.
    http://dx.doi.org/10.1186/1471-2180-14-167.
  3. Kiga K, Fukuda-Yuzawa Y, Tanabe M, Tsuji S, Sasakawa C, Fukao T. Comprehensive silencing of target-sharing microRNAs is a mechanism for SIRT1 overexpression in cancer. RNA Biology 2014; 11:1347-1354.
    http://dx.doi.org/10.4161/rna.32093.
  4. Tasaka S, Kobayashi S, Yagi K, Asami T, Namkoong H, Yamasawa W, Ishii M, Hasegawa N, Betsuyaku T. Serum (1 → 3) β-D-glucan assay for discrimination between Pneumocystis jirovecii pneumonia and colonization. J Infect Chemother. 2014;20:678-681.
    http://dx.doi.org/10.1016/j.jiac.2014.07.001.
  5. Shiragami M, Mizukami A, Leeuwenkamp O, Mrkvan T, Delgleize E, Kurono Y, Iwata S. Cost-Effectiveness Evaluation of the 10-Valent Pneumococcal Non-typeable Haemophilus influenzae Protein D Conjugate Vaccine and 13-Valent Pneumococcal Vaccine in Japanese Children. Infect Dis Ther. 2014;4:93-112.
    http://dx.doi.org/10.1007/s40121-014-0053-7.
  6. Mori T, Hasegawa N, Sugita K, Shinjoh M, Nakamoto N, Shimizu T, Hori S, Iketani O, Fujiwara H, Takano Y, Iwata S. Clinical features of bacteremia due to Campylobacter jejuni. Intern Med. 2014;53:1941-1944.
    http://dx.doi.org/10.2169/internalmedicine.53.2559.
  7. Funatsu Y, Hasegawa N, Fujiwara H, Namkoong H, Asami T, Tasaka S, Kimizuka Y, Kamata H, Ishii M, Iketani O, Ogata H, Iwata S, Betsuyaku T.: Pharmacokinetics of arbekacin in bronchial epithelial lining fluid of healthy volunteers. J Infect Chemother. 2014;20:607-611.
    http://dx.doi.org/10.1016/j.jiac.2014.05.007.
  8. Chiba N, Morozumi M, Michi Shouji M, Wajima T, Iwata S, Ubukata K, The Invasive Pneumococcal Diseases Surveillance Study Group. Changes in capsule and drug resistance of pneumococci after introduction of PCV7, Japan, 2010–2013. Emerg Infect Dis. 2014; 20:1132-1139.
    http://dx.doi.org/10.3201/eid2007.131485.
  9. Morozumi M, Wajima T, Kuwata Y, Chiba N, Sunaoshi K, Sugita K, Sakata H, Iwata S, Ubukata K. Associations between capsular serotype, multilocus sequence type, and macrolide resistance in Streptococcus agalactiae isolates from Japanese infants with invasive infections. Epidemiol Infect. 2014;142:812-819.
    http://dx.doi.org/10.1017/S0950268813001647.
  10. Morozumi M, Shimizu H, Matsushima Y, Mitamura K, Tajima T, Iwata S, Ubukata K. Evaluation of new immunochromatographic assay kit for adenovirus detection in throat swab: Comparison with culture and real-time PCR results. J Infect Chemother. 2014; 20:303-306.
    http://dx.doi.org/10.1016/j.jiac.2014.01.005.
  11. Wajima T, Chiba N, Morozumi M, Shouji M, Sunaoshi K, Sugita K, Tajima T, Ubukata K, GAS Surveillance Study Group. Prevalence of macrolide resistance among Group A streptococci Isolated from pharyngotonsillitis. Microb Drug Resist. 2014;20:431-435.
    http://dx.doi.org/10.1089/mdr.2013.0213.
  12. Morita A, Kamei S, Minami M, Yoshida K, Kawabata S, Kuroda H, Suzuki Y, Araki N, Iwasaki Y, Kobayashi R, Hayashi N, Hirayama T, Ochiai J, Ueda M, Yamagishi Y, Niwa JI, Shindo K, Fukushima Y, Takita T, Sato T, Sato S, Mikamo H, Iwata S. Open-label study to evaluate the pharmacodynamics, clinical efficacy, and safety of meropenem for adult bacterial meningitis in Japan. J Infect Chemother. 2014;20:535-540.
    http://dx.doi.org/10.1016/j.jiac.2014.04.013.
  13. Shinjoh M, Iwata S, Yagihashi T, Sato Y, Akita H, Takahashi T, Sunakawa K. Recent trends in pediatric bacterial meningitis in Japan - A country where Haemophilus influenzae type b and Streptococcus pneumoniae conjugated vaccines have just been introduced. J Infect Chemother. 2014;20:477-483.
    http://dx.doi.org/10.1016/j.jiac.2014.04.007.
  14. Namkoong H, Kameyama Y, Yasuda H, Nakayama S, Kaneko H, Kawashima C, Terajima T, Maezawa K, Hayashi T, Sandoh M, Ishii M, Tasaka S, Kanayama A, Kobayashi I, Betsuyaku T, Kizu J, Iwata S, Sato Y, Hasegawa N.: The efficacy, safety, and pharmacokinetics of biapenem administered thrice daily for the treatment of pneumonia in the elderly. J Infect Chemother. 2014 ; 20:356-360.
    http://dx.doi.org/10.1016/j.jiac.2013.12.010.
  15. Kawajiri H, Aeba R, Takaki H, Yozu R, Iwata S.: Negative pressure therapy for post-sternotomy wound infections in young children. Interact Cardiovasc Thorac Surg. 2014; 19:102-106.
    http://dx.doi.org/10.1093/icvts/ivu050.
  16. Mikita K, Maeda T, Yoshikawa S, Ono T, Miyahira Y, Kawana A. The Direct Boil-LAMP method: a simple and rapid diagnostic method for cutaneous leishmaniasis. Parasitol Int. 2014; 63(6): 785-9.
  17. Kawano S, Maeda T, Watanabe J, Fujikura Y, Mikita K, Hara Y, Kanoh S, Kimura F, Miyahira Y, Kawana A.Successful diagnosis of tuberculous lymphadenitis by loop-mediated isothermal amplification of cutaneous samples from an ulcerated surface lesion: a case report. J Med Case Rep. 2014.; 16(8): 254
  18. Mikita K, Thakur K, Anstey NM, Piera KA, Pardo CA, Weinberg JB, Mukemba J, Florence S, Mwaikambo ED, Granger DL, Sullivan DJ. Quantification of Plasmodium falciparum histidine-rich protein-2 in cerebrospinal spinal fluid from cerebral malaria patients. Am J Trop Med Hyg. 2014; 91(3): 486-92.
  19. Sakamoto N, Maeda T, Mikita K, Kato Y, Yanagisawa N, Suganuma A, Imamura A, Nakamura-Uchiyama F, Miyahira Y, Kawana A, Ohnishi K, Ajisawa A. Clinical presentation and diagnosis of toxoplasmic encephalitis in Japan. Parasitol Int. 2014; 63(5): 701-4.
  20. Imai K, Maeda T, Sayama Y, Mikita K, Fujikura Y, Misawa K, Nagumo M, Iwata O, Ono T, Kurane I, Miyahira Y, Kawana A, Miura S. Mother-to-child transmission of congenital Chagas disease, Japan. Emerg Infect Dis. 2014; 20(1): 146-8.

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Research and Achievements