研究・業績

2021年度

2021年度業績

  1. Akahane M, Enoki Y, Saiki R, Hayashi Y, Hiraoka K, Honma K, Itagaki M, Gotoda M, Shinoda K, Hanyu S, Hamamura Y, Miyajima T, Ito C, Taguchi K, Uno S, Uwamino Y, Iketani O, Hasegawa N, Matsumoto K. Stability of antimicrobial agents in an elastomeric infusion pump used for outpatient parenteral antimicrobial therapy. Int J Infect Dis. 103:464-468,2021.
  2. Uchida S, Uno S, Uwamino Y, Hashimoto M, Matsumoto S, Obara M, Kitagawa Y, Hasegawa N,Keio Donner Project Team. CT screening for COVID-19 in asymptomatic patients before hospital admission. J Infect Chemother.27(2):232-236,2021.
  3. Asakura T, Kimizuka Y, Nishimura T, Suzuki S, Namkoong H, Masugi Y, Sato Y, Ishii M, Hasegawa N. Serum Krebs von den Lungen-6 level in the disease progression and treatment of Mycobacterium avium complex lung disease. Respirology. 26(1):112-119, 2021.
  4. Yoshida M, Sano S, Chien JY, Fukano H, Suzuki M, Asakura T, Morimoto K, Murase Y, Miyamoto S, Kurashima A, Hasegawa N, Hsueh PR, Mitarai S, Ato M, Hoshino Y. A novel DNA chromatography method to discriminate Mycobacterium abscessus subspecies and macrolide susceptibility. EBioMedicine. 64:103187, 2021.
  5. Uwamino Y, Wakui M, Aoki W, Kurafuji T, Yanagita E, Morita M, Nagata M, Inose R, Noguchi M, Yokota H, Hasegawa N, Saya H, Murata M; Keio Donner Project Team. Evaluation of the usability of various rapid antibody tests in the diagnostic application for COVID-19. Ann Clin Biochem..4563220984827,2021.
  6. Abe K, Shimura T, Takenouchi T, Iwasaki YW, Ishizu H, Uwamino Y, Uno S, Gotoh J, Tachikawa N, Takeuchi Y, Katayama J, Nozaki H, Fujii S, Seki S, Nakamura M, Uda K, Misumi T, Ishihara J, Yamada K, Kanai T, Murai S, Araki K, Ebihara T, Siomi H, Hasegawa N, Kitagawa Y, Amagai M, Suematsu M, Kosaki K. Identification of B.1.346 Lineage of SARS-CoV-2 in Japan: Genomic Evidence of Re-entry of Clade 20C. Keio J Med, 2021
  7. Wakui M, Uwamino Y, Kurafuji T, Noguchi M, Ohno A, Yokota H, Kikuchi H, Hasegawa N, Saya H, Murata M, the Keio Donner Project Team. Assessment of humoral responses in COVID-19 using various quantitative antibody tests. Ann Clin Biochem. 45632211006740, 2021.
  8. Kondo Y, Kaneko Y, Takei H, Tamai H, Kabata H, Suhara T, Yamamoto R, Nagata H, Ishii M, Sasaki J, Hasegawa N, Fukunaga K, Takeuchi T; Keio Donner Project. COVID-19 shares clinical features with anti-melanoma differentiation-associated protein 5 positive dermatomyositis and adult Still's disease. Clin Exp Rheumatol. Online ahead of print.PMID: 33886458, 2021.
  9. Namkoong H, Omae Y, Asakura T, Ishii M, Suzuki S, Morimoto K, Kawai Y, Emoto K, Oler AJ, Szymanski EP, Yoshida M, Matsuda S, Yagi K, Hase I, Nishimura T, Sasaki Y, Asami T, Shiomi T, Matsubara H, Shimada H, Hamamoto J, Jhun BW, Kim SY, Huh HJ, Won HH, Ato M, Kosaki K, Betsuyaku T, Fukunaga K, Kurashima A, Tettelin H, Yanai H, Mahasirimongkol S, Olivier KN, Hoshino Y, Koh WJ, Holland SM, Tokunaga K, Hasegawa N. Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease.N. Eur Respir J. 1902269, 2021.
  10. Yagi K, Ito A, Fujiwara K, Morino E, Hase I, Nakano Y, Asakura T, Furuuchi K, Morita A, Asami T, Namkoong H, Saito F, Morimoto K, Ishii M, Sato Y, Tateno H, Nishio K, Oyamada Y, Fukunaga K, Sugiyama H, Ishida T, Kurashima A, Hasegawa N; Nontuberculous mycobacteriosis and bronchiectasis- Japan Research Consortium (NTM-JRC). Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis: A Multicenter Retrospective Study. Ann Am Thorac Soc. Online ahead of print, 2021.
  11. Fukushima T, Kabata H, Yamamoto R, Suhara T, Uwamino Y, Kondo Y, Masaki K, Kamata H, Nagata H, Homma K, Kaneko Y, Ishii M, Sasaki J, Morisaki H, Hasegawa N, Fukunaga K; Keio Donner Project Team. The real-time reverse transcription-polymerase chain reaction threshold cycle values for severe acute respiratory syndrome coronavirus 2 predict the prognosis of coronavirus disease 2019 pneumonia. Respir Investig. 59(3):360-363, 2021.
  12. Kawakami N, Kawai M, Namkoong H, Arai D, Ueda S, Hamada K, Kawada I, Hasegawa N, Mikami S, Asamura H, Fukunaga K. Cardiac tamponade due to primary malignant pericardial mesothelioma diagnosed with surgical pericardial resection. J Cardiol Cases.24(4):149-152, 2021.
  13. Tanaka H, Lee H, Morita A, Namkoong H, Chubachi S, Kabata H, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K; Japan COVID-19 Task Force. Clinical Characteristics of Patients with Coronavirus Disease (COVID-19): Preliminary Baseline Report of Japan COVID-19 Task Force, a Nationwide Consortium to Investigate Host Genetics of COVID-19. Int J Infect Dis. 113:74-81,2021.
  14. Ogawa T, Asakura T, Suzuki S, Okamori S, Kusumoto T, Sato Y, Namkoong H, Kamata H, Ishii M, Fukunaga K, Hasegawa N. Longitudinal validity and prognostic significance of the St George's Respiratory Questionnaire in Mycobacterium avium complex pulmonary disease. Respir Med. 185:106515,2021.
  15. Okamori S, Ishii M, Asakura T, Suzuki S, Namkoong H, Kagawa S, Hegab AE, Yagi K, Kamata H, Kusumoto T, Ogawa T, Takahashi H, Yoda M, Horiuchi K, Hasegawa N, Fukunaga K. ADAM10 partially protects mice against influenza pneumonia by suppressing specific myeloid cell population. Am J Physiol Lung Cell Mol Physiol. 321(5):L872-L884,2021.
  16. Nakagawara K, Namkoong H, Terai H, Masaki K, Tanosaki T, Shimamoto K, Lee H, Tanaka H, Okamori S, Kabata H, Chubachi S, Ikemura S, Kamata H, Yasuda H, Kawada I, Ishii M, Ishibashi Y, Harada S, Fujita T, Ito D, Bun S, Tabuchi H, Kanzaki S, Shimizu E, Fukuda K, Yamagami J, Kobayashi K, Hirano T, Inoue T, Kagyo J, Shiomi T, Ohgino K, Sayama K, Otsuka K, Miyao N, Odani T, Oyamada Y, Masuzawa K, Nakayama S, Suzuki Y, Baba R, Nakachi I, Kuwahara N, Ishiguro T, Mashimo S, Minematsu N, Ueda S, Manabe T, Funatsu Y, Koh H, Yoshiyama T, Saito F, Ishioka K, Takahashi S, Nakamura M, Goto A, Harada N, Kusaka Y, Nakano Y, Nishio K, Tateno H, Edahiro R, Takeda Y, Kumanogoh A, Kodama N, Okamoto M, Umeda A, Hagimura K, Sato T, Miyazaki N, Takemura R, Sato Y, Takebayashi T, Nakahara J, Mimura M, Ogawa K, Shimmura S, Negishi K, Tsubota K, Amagai M, Goto R, Ibuka Y, Hasegawa N, Kitagawa Y, Kanai T, Fukunaga K. Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol. BMJ Open Respir Res. 8(1):e001015,2021.
  17. Takenouchi T, Iwasaki WY, Harada S, Ishizu H, Uwamino Y, Uno S, Osada A, Abe K, Hasegawa N, Murata M, Takebayashi T, Fukunaga K, Saya H, Kitagawaga Y, Amagai M, Siomi H, Kosaki K, Keio Donner Project. Clinical utility of SARS-CoV-2 whole genome sequencing in deciphering source of infection. J Hosp Infect. 107: 40-4, 2021.
  18. Uno S, Nishimura T, Nishio K, Kohsaka A, Tamizu E, Nakano Y, Kagyo J, Nakajima Y, Arai R, Hasegawa H, Arakawa K, Kashimura S, Ishii R, Miyazaki N, Uwamino Y, Hasegawa N. Potential biomarker enhancing the activity of tuberculosis, hsa-miR-346. Tuberculosis. 129: 102101,2021.
  19. Nishimura T, Uwamino Y, Uno S, Kashimura S, Shiraki T, Kurafuji T, Morita M, Noguchi M, Azegami T, Yamada-Goto N, Murai-Takeda A, Yokoyama H, Kuwabara K, Kato S, Matsumoto M, Hirata A, Iida M, Harada S, Ishizaka T, Misawa K, Murata M, Saya H, Amagai M, Kitagawa Y, Takeuchi T, Mori M, Takebayashi T, Hasegawa N; Keio Donner Project Team. SARS-CoV-2 Infection among Medical Institution Faculty and Healthcare Workers in Tokyo, Japan. Intern Med. 60: 2569-75, 2021.
  20. Misawa K, Iketani O, Enoki Y, Taguchi K, Uno S, Uwamino Y, Hasegawa N, Matsumoto K. Retrospective study of the efficacy and safety of metronidazole and vancomycin for Clostridioides difficile infection. J Infect Chemother. 27: 1407-12,2021.
  21. Uchida S, Uwamino Y*, Uno S, Nagata M, Aoki W, Murata M, Kitagawa Y, Hasegawa N; Keio Donner Project Team. Universal Polymerase Chain Reaction Screening for Severe Acute Respiratory Syndrome Coronavirus 2 in Asymptomatic Patients Before Hospital Admission in Tokyo, Japan. J Clin Virol. 142: 104915,2021.
  22. Takei H, Nishina N, Namkoong H, Suzuki K, Uwamino Y, Hasegawa N, Takeuchi T. Rheumatoid Arthritis with Nontuberculous Mycobacterial Pulmonary Disease: A Retrospective, Single-center Cohort Study. Modern Rheumatol. 12; roab032, 2021.
  23. COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature. 600:472-7,2021.
  24. Yokoyama T, Nishimura T, Uwamino Y, Kosaki K, Furusaki K, Onishi R, Onodera T, Haritani M, Sugiura K, Kirisawa R, Hasegawa N. Virucidal Effect of the Mesoscopic Structure of CAC-717 on Severe Acute Respiratory Syndrome Coronavirus-2. Microorganisms. 9: 2096, 2021.
  25. Sekiguchi K, Watanabe N, Miyazaki N, Ishizuchi K, Iba C, Tagashira Y, Uno S, Shibata M, Hasegawa N, Takemura R, Nakahara J, Takizawa T. Incidence of headache after COVID-19 vaccination in patients with history of headache: A cross-sectional study. Cephalalgia. 3331024211038654, 2021.
  26. Fukuda N, Horita N, Katakura S, Namkoong H, Kaneko A, Somekawa K, Tagami Y, Watanabe K, Hara Y, Kobayashi N, Kaneko T. The best regimens for chemo-naïve incurable non-squamous non-small cell lung cancer with a programmed death-ligand 1, tumor proportion score 1-49%: a network meta-analysis. Transl Lung Cancer Res. 2021 Aug;10(8):3550-3566.
  27. Sasahara K, Kitahama K, Aiko S, Namkoong H. Anal tuberculosis presenting as refractory perianal abscess. Clin Case Rep. 2021 Jun 26;9(9):e04177.
  28. Fujiwara Y, Horita N, Namkoong H, Galsky MD. The effect of adding immune checkpoint inhibitors on the risk of pneumonitis for solid tumours: a meta-analysis of phase III randomised controlled trials. Eur J Cancer. 2021 Apr 24;150:168-178.
  29. Hosoda T, Mikita K, Ito M, Nagasaki H, Sakamoto M Cerebral toxoplasmosis with multiple hemorrhage lesions in an HIV infected patient: A case report and literature review. Parasitol Int. 2021 Apr;81:102280.
  30. Amikura T, Kikuchi T, Kato J, Koda Y, Sakurai M, Yamazaki R, Mikita K, Saburi M, Nakazato T, Mori T Toxoplasmosis after allogeneic hematopoietic stem cell transplantation: Impact of serostatus-based management. Transpl Infect Dis. 2021 Jun;23(3):e13506.
  31. Takeshita M, Nishina N, Moriyama S, Takahashi Y, Uwamino Y, Nagata M, Aoki W, Masaki K, Ishii M, Saya H, Kondo Y, Kaneko Y, Suzuki K, Fukunaga K, Takeuchi T; Keio Donner project. Incomplete humoral response including neutralizing antibodies in asymptomatic to mild COVID-19 patients in Japan. Virology. 2021; 555: 35-43
  32. Hamada N, Maeda A, Takase-Minegishi K, Kirino Y, Sugiyama Y, Namkoong H, Horita N, Yoshimi R, Nakajima H; YCU irAE Working Group. Incidence and Distinct Features of Immune Checkpoint Inhibitor-Related Myositis From Idiopathic Inflammatory Myositis: A Single-Center Experience With Systematic Literature Review and Meta-Analysis. Front Immunol. 2021 Dec 6;12:803410.
  33. Sato Y, Atarashi K, Plichta RD, Arai Y, Sasajima S, Kearney MS, Suda W, Takeshita K, Sasaki T, Okamoto S, Skelly NA,Okamura Y, Vlamakis H, Li Y, Tanoue T, Takei H, Nittono H, Narushima S, Irie J, Itoh H, Moriya K, Sugiura Y, Suematsu M, Moritoki N, Shibata S, Littman RD, Fischbach AM, Uwamino Y, Takashi Inoue, Akira Honda, Masahira Hattori, Murai T, Xavier JR, Hirose N, Honda K. Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians. Nature. 2021, 599: 458-64.
  34. Iizuka Y, Takase-Minegishi K, Hirahara L, Kirino Y, Soejima Y, Namkoong H, Horita N, Yoshimi R, Takeuchi M, Takeno M, Mizuki N, Nakajima H. Beneficial Effects of Apremilast on Genital Ulcers, Skin Lesions, and Arthritis in Patients With Behçet's Disease: A Systematic Review and Meta-Analysis. Mod Rheumatol. 2021 Nov 10:roab098.
  35. Uno S, Uehara E, Kimura T, Sakagami T, Namkoong H, Uchida S, Uwamino Y, Hasegawa N. R-CHOP chemotherapy for disseminated Mycobacterium avium complex disease due to anti-interferon-gamma autoantibodies: A case report. Open Forum Infect Dis. 8(6):ofab181,2021.
  36. Uno S, Takano Y, Iketani O, Abiko T, Miwa T, Nanki K, Kurihara T, Tamura Y, Ara M, Uwamino Y, Shinjoh M, Mori T, Hasegawa N. Digestive decolonization of colorectal carriage of vancomycin-resistant Enterococcus faecium in a Japanese adult: A case report. Intern Med. 6088-20, 2021.
  37. Matoba Y, Nishio H, Sekiguchi K, Uno S, Masuda K, Hiramatsu M, Takahashi M, Oishi M, Uwamino Y, Uchida S, Daté Y, Morisada T, Banno K, Nakahara J, Aoki D. Meningitis caused by Listeria monocytogenes in a locally advanced cervical cancer patient with pyometra: A case report. Gynecol Oncol Rep. 2021 May 29;37:100799. doi: 10.1016/j.gore.2021.100799.
  38. Furuichi Y, Ito Y, Tanese K, Mukai M, Uwamino Y, Hasegawa N, Amagai M, Umegaki-Arao N. Two case reports of Mycobacterium marinum infection with psoriatic arthritis treated by tumor necrosis factor-α inhibitors. J Dermatol. 48(2):e106-e107,2021.